snip20161017_19

Antimicrobial Coumarin Derivative from Delonix regia

Abstract

The dichloromethane extract of the air-dried leaves of Delonix regia afforded scopoletin (1) by silica gel chromatography. The structure of 1 was determined by spectroscopic methods and confirmed by comparison of its 1H NMR data with those reported in the literature for scopoletin. Compound 1 exhibited antifungal activity against Candida albicans and antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, and Bubtilis subtilis. It was inactive against the fungi, Aspergillus niger and Trichophyton mentagrophytes.

Antimicrobial Coumarin Derivative from Delonix regia (131.7 KiB)