The chloroform extract of the air-dried leaves of Vitex parviflora afforded retusin by silica gel chromatography. Its structure was elucidated by extensive ID and 2D NMR spectroscopy. Antimicrobial tests indicated that retusin has moderate activity against the fungi, A. niger and low activity against the bacteria, P. aeruginosa. It was found inactive against the fungi, C. albicans and T. mentagrophytes and the bacteria: E. coli, S. aureus and B. subtilis.
A Flavone from Vitex parviflora (323.2 KiB)